First Southern Bank in St. Florian, AL is located at and angled toward the intersection of Old Jackson Highway and St. Florian Road. Offices, tellers, and a post room are organized around a central teller lobby, and a drive-through with three lanes and a night deposit box is at the rear of the building. The exterior is traditional in style and has a neutral color palette of warm grays. Lap siding, square columns, and rounded windows complete the traditional look.